Optogenetics is a technique where optically activated proteins are used to control neuronal function. This is part of recent neuroscientific developments that offer treatment options for incurable diseases, including retinal disease, Alzheimer’s disease, and Parkinson’s disease. Optogenetic techniques allow the inhibition or activation of specific neurons with a high degree of temporal, neurochemical and spatial precision. As part of the technique, the gene whose light-sensitive protein code is removed from algae species. The protein actually acts as an ion channel that closes or opens in response to a particular light. This gene which codes for this protein is placed in the specific neuron of the brain and it is expressed to produce the light sensitive protein. When the light flashes on a particular neural cell, the neural signal is conducted. The technique could be used to control the movement of neurons and to understand how brain cells work at the cellular level.
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Global Optogenetic Actuators and Sensors Market – Market Dynamics
The increasing prevalence of neurological disorders and retinal diseases, the rapid R&D in the field of optogenetics, and the government funding initiatives to support the development of this field, are some of the players responsible for the growth of the global actuator market. and optogenetic sensors, during the forecast period. Optogenetics provides an understanding of which physiological and biochemical pathway works to cause a particular disease, potentially helping to find a cure for a particular disease through the blue light flashing on particular neural cells. According to the 2016 fact sheet of the World Health Organization fact sheet, age-related macular degeneration (AMD) was the third leading cause of visual impairment in the world, with blindness being 8, 7%. AMD mainly causes visual impairment in developed countries. Another potential segment is Alzheimer’s disease where optogenetics could offer a lasting solution for treatment. According to the World Alzheimer’s Disease Report 2016, there were approximately 46.5 million Alzheimer’s disease patients worldwide. In addition, worldwide, one last case of Alzheimer’s disease is recorded every 3 seconds.
Global Optogenetics Actuators and Sensors Market – Regional Outlook
Based on geography, global Optogenetic actuators and sensors market is separated into North America, Europe, Latin America, Asia-Pacific, Africa and the Middle East. North America is expected to dominate the global optogenetic actuators and sensors market during the forecast period. The majority of optogenetics-related research is ongoing in the United States, so it provides a favorable growth environment for the market. Governments are increasingly funding R&D activities in this sector, as optogenetics potentially offer a better understanding of the pathophysiology of chronic neural diseases, including Parkinson’s and Alzheimer’s diseases, which have a high prevalence rate in patients. United States. For example, in 2016, the National Institute of Mental Health of the National Institutes of Health (NIH) awarded US $ 1.4 million for optogenetic research at the Max Planck Florida Institute for Neuroscience and NYU Langone Medical Center. Companies such as GenSight Biologics have their Optogenetics-GS030 research platform at the preclinical stage.
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Global Optogenetics Actuators and Sensors Market – Competitive Landscape
The major players operating in the Optogenetic Actuators and Sensors market include Bruker, Gensight Biologics, Circuit Therapeutics, Inc., AGTC, Merck KGaA, Prizmatix, Elliot Scientific Ltd., The Jackson Laboratory, Coherent, Inc., Scientifica (Judges Scientific Plc Company), Shanghai Laser & Optics Century Co., Ltd. (SLOC), Addgene, Noldus Information Technology, Danaher and Thorlabs, Inc.
Global Optogenetic Actuators and Sensors Market – Market Taxonomy
Based on actuators,
Based on sensors,
- Voltage-sensitive fluorescent proteins
- Genetically encoded calcium indicators
- PH sensors
- Light emitting diode
Depending on the applications,
- Retinal disorder
- Psychological disorder
- Neuronal disorder
Based on geography,
- North America
- Latin America
- Asia Pacific
- Middle East
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